Recurrent secondary genomic alterations in desmoplastic small round cell tumors.

Desmoplastic small round cell tumor (DSRCT) is a rare, highly aggressive, translocation-associated soft-tissue sarcoma that primarily affects children, adolescents, and young adults, with a striking male predominance. It is characterized by t(11;22) generating a novel EWSR1-WT1 fusion gene. Secondary genomic alterations are rarely described.Tumor tissue from 83 DSRCT patients was assayed by hybrid-capture based comprehensive genomic profiling, FoundationOne Heme next generation sequencing analysis of 406 genes and RNA sequencing of 265 genes.

Tumor mutation burden was calculated from a minimum of 1.4 Mb sequenced DNA. Microsatellite instability status was determined by a novel algorithm analyzing 114 specific loci.Comprehensive genomic profiling identified several genomically-defined DSRCT subgroups.

Recurrent genomic alterations were most frequently detected in FGFR4, ARID1A, TP53, MSH3, and MLL3 genes. With the exception of FGFR4, where the genomic alterations predicted activation, most of the alterations in the remaining genes predicted gene inactivation.

No DSRCT were TMB or MSI high.In summary, recurrent secondary somatic alterations in FGFR4, ARID1A, TP53, MSH3, and MLL3 were detected in 82% of DSRCT, which is significantly greater than previously reported. These alterations may have both prognostic and therapeutic implications.

Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)
TA308900	Origene Technologies GmbH	100 µl	Ask for price

Haptamide B
T25488-10mg	TargetMol Chemicals	10mg	Ask for price
Description: Haptamide B

Haptamide B
T25488-1g	TargetMol Chemicals	1g	Ask for price
Description: Haptamide B

Haptamide B
T25488-1mg	TargetMol Chemicals	1mg	Ask for price
Description: Haptamide B

Haptamide B
T25488-50mg	TargetMol Chemicals	50mg	Ask for price
Description: Haptamide B

Haptamide B
T25488-5mg	TargetMol Chemicals	5mg	Ask for price
Description: Haptamide B

Interleukin-11 (IL-11)
GWB-867D56	GenWay Biotech	0.01 mg	Ask for price

MitoBloCK-11 (MB-11)
T8782-10mg	TargetMol Chemicals	10mg	Ask for price
Description: MitoBloCK-11 (MB-11)

MitoBloCK-11 (MB-11)
T8782-1g	TargetMol Chemicals	1g	Ask for price
Description: MitoBloCK-11 (MB-11)

MitoBloCK-11 (MB-11)
T8782-1mg	TargetMol Chemicals	1mg	Ask for price
Description: MitoBloCK-11 (MB-11)

MitoBloCK-11 (MB-11)
T8782-50mg	TargetMol Chemicals	50mg	Ask for price
Description: MitoBloCK-11 (MB-11)

MitoBloCK-11 (MB-11)
T8782-5mg	TargetMol Chemicals	5mg	Ask for price
Description: MitoBloCK-11 (MB-11)

OPPA01435-200UG - Haptoglobin Human - Human Haptoglobin Protein
OPPA01435-200UG	Aviva Systems Biology	200ug	EUR 112

Haptoglobin
E8ET1703-24	EnoGene	100ul	EUR 275
Description: Available in various conjugation types.

Haptoglobin
E8M1510-36	EnoGene	100ul	EUR 275
Description: Available in various conjugation types.

Haptoglobin
E8M1510-37	EnoGene	100ul	EUR 275
Description: Available in various conjugation types.

Haptoglobin
AP78677	SAB	1mg	EUR 2640

Haptoglobin
AP83683	SAB	1mg	EUR 2640

Haptoglobin
AP83875	SAB	1mg	EUR 2640

Haptoglobin
AP83959	SAB	1mg	EUR 2640

Haptoglobin
AP84082	SAB	1mg	EUR 2640

Haptoglobin
AP84671	SAB	1mg	EUR 2640

Haptoglobin (19-347)
pro-1897	ProSpec Tany	2µg	EUR 60
Description: Recombinant Human Haptoglobin (19-347 a.a)

Haptoglobin
pro-567	ProSpec Tany	5µg	EUR 60
Description: Recombinant Human Haptoglobin

Rat Haptoglobin (Hp)
1-CSB-RP170694r	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Rat Haptoglobin(Hp),partial expressed in E.coli

Rat Haptoglobin
8110	Life Diagnostics	0.1 mg	EUR 220

Dog Haptoglobin
8120	Life Diagnostics	0.1 mg	EUR 220

Pig Haptoglobin
8130	Life Diagnostics	0.1 mg	EUR 220

Haptoglobin, Sf9
pro-2586	ProSpec Tany	2µg	EUR 60
Description: Recombinant Human Haptoglobin, Sf9

Human Haptoglobin
7-05311	CHI Scientific	200µg	Ask for price

Human Haptoglobin
7-05312	CHI Scientific	1mg	Ask for price

Human Haptoglobin
7-05313	CHI Scientific	10mg	Ask for price

Mouse Haptoglobin
8140	Life Diagnostics	0.1 mg	EUR 220

Horse Haptoglobin
8150	Life Diagnostics	1 mg	EUR 275

Human Haptoglobin (HP)
1-CSB-EP010691HU	Cusabio	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	100ug 10ug 1MG 200ug 500ug 50ug
Description: Recombinant Human Haptoglobin(HP) expressed in E.coli

Haptoglobin Mixed 95%
GWB-D29DCE	GenWay Biotech	2 mg	Ask for price

Haptoglobin Human
rAP-3368	Angio Proteomie	Inquiry	Ask for price

Haptoglobin Assay Kit
abx098432-BeckmanR140ml1R210ml1	Abbexa	Beckman; R1: 40ml×1 R2: 10ml×1	EUR 416.4

Haptoglobin Assay Kit
abx098432-Hitachi7020R140ml1R210ml1	Abbexa	Hitachi 7020; R1: 40ml×1 R2: 10ml×1	EUR 416.4

Haptoglobin Assay Kit
abx098432-Hitachi7170R120ml1R25ml1	Abbexa	Hitachi 7170; R1: 20ml×1 R2: 5ml×1	EUR 322.8

Haptoglobin Assay Kit
abx098432-Toshiba40R140ml1R210ml1	Abbexa	Toshiba 40; R1: 40ml×1 R2: 10ml×1	EUR 416.4

Rabbit Haptoglobin
8175	Life Diagnostics	0.1 mg	EUR 220

Rat Haptoglobin (HP) CLIA Kit
abx195771-96tests	Abbexa	96 tests	EUR 990

Cow Haptoglobin (HP) CLIA Kit
20-abx492072	Abbexa	Ask for price Ask for price Ask for price	10 × 96 tests 5 × 96 tests 96 tests

Bovine Haptoglobin
8010	Life Diagnostics	1 mg	EUR 880

Haptoglobin ELISA kit
55R-1873	Fitzgerald	1 kit	EUR 891.6
Description: ELISA kit for the detection of Haptoglobin in the research laboratory

Haptoglobin ELISA, Rat
KT-190	Kamiya Biomedical Company	96 tests	EUR 506

Haptoglobin, Bovine
KT-191	Kamiya Biomedical Company	1 kit	EUR 506

Pig Haptoglobin ELISA
KT-349	Kamiya Biomedical Company	1 kit	EUR 506

Cat Haptoglobin ELISA
KT-422	Kamiya Biomedical Company	96 tests	EUR 537

Haptoglobin Mouse mAb
E2M50010	EnoGene	100ul	EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Rat HP -Haptoglobin- CLIA Kit
E-CL-R0320-24Tests	Elabscience Biotech	24 Tests	EUR 180
Description: Sandwich

Rat HP -Haptoglobin- CLIA Kit
E-CL-R0320-48Tests	Elabscience Biotech	48 Tests	EUR 546
Description: Sandwich

Rat HP -Haptoglobin- CLIA Kit
E-CL-R0320-96Tests	Elabscience Biotech	96 Tests	EUR 682
Description: Sandwich

Rat HP -Haptoglobin- CLIA Kit
E-CL-R0320-96Tests10	Elabscience Biotech	96 Tests *10	EUR 6820
Description: Sandwich

Rat HP -Haptoglobin- CLIA Kit
E-CL-R0320-96Tests5	Elabscience Biotech	96 Tests *5	EUR 3410
Description: Sandwich

Haptoglobin ELISA Kit
80714	Crystal Chem	96	EUR 425

(19-347) Haptoglobin (19-347 a.a) Human Recombinant Protein
PROTP00738-2	BosterBio	Regular: 10ug	EUR 380.4
Description: Haptoglobin Human Recombinant produced in E. coli is a single polypeptide chain containing 352 amino acids (19-347) and having a molecular mass of 39.0 kDa. Haptoglobin is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Calpain 11 (Calpain 11) Antibody
20-abx111329	Abbexa	Ask for price Ask for price	150 ul 50 ul

11-Hydroxyprogesterone (11-OHP) Antibody
20-abx102405	Abbexa	Ask for price Ask for price Ask for price Ask for price Ask for price	100 ug 10 ug 1 mg 200 ug 50 ug

Calpain 11 (Calpain 11) Antibody
20-abx121925	Abbexa	Ask for price Ask for price Ask for price	100 ul 200 ul 30 ul

Kallikrein 11 (Kallikrein 11) Antibody
20-abx007794	Abbexa	Ask for price Ask for price Ask for price	100 ul 200 ul 30 ul

Kallikrein 11 (Kallikrein 11) Antibody
20-abx008292	Abbexa	Ask for price Ask for price Ask for price	100 ul 200 ul 30 ul

Kallikrein 11 (Kallikrein 11) Antibody
abx234457-100ug	Abbexa	100 ug	EUR 577.2

Calpain 11 (Calpain 11) Antibody
abx231212-100ug	Abbexa	100 ug	EUR 577.2

Syntaxin 11 (Syntaxin 11) Antibody
abx431886-200ul	Abbexa	200 ul	EUR 460.8

Syntaxin 11 (Syntaxin 11) Antibody
abx238445-100ug	Abbexa	100 ug	EUR 610.8

11-Chloro-11-oxoundecyl Methanesulfonate
C368355	Toronto Research Chemicals	100mg	EUR 546

IL-11, Interleukin-11, human
RC212-22	Bio Basic	2ug	EUR 125.26

11-Hydroxyprogesterone (11-OHP) Antibody
abx102405-100l	Abbexa	100 µl	EUR 287.5

11-Hydroxyprogesterone (11-OHP) Antibody
abx102405-1ml	Abbexa	1 ml	EUR 850

11-Hydroxyprogesterone (11-OHP) Antibody
abx102405-200l	Abbexa	200 µl	EUR 375

Haptoglobin Rabbit mAb
59347	SAB	100ul	EUR 339

Rat Haptoglobin (HP) ELISA Kit
abx051814-96tests	Abbexa	96 tests	EUR 904.8

Pig Haptoglobin (HP) ELISA Kit
abx051815-96tests	Abbexa	96 tests	EUR 943.2

Haptoglobin (HP) Rabbit mAb
A8778	Abclonal	200μL	EUR 1557.4
Description: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RNF20 (Q5VTR2).

Haptoglobin protein
30-AH02	Fitzgerald	1 mg	EUR 144
Description: Purified native Human Haptoglobin protein

Haptoglobin protein
30C-CP3018	Fitzgerald	1 mg	EUR 180
Description: Purified native Human Haptoglobin protein

Pig Haptoglobin (HP) ELISA Kit
abx255484-96tests	Abbexa	96 tests	EUR 943.2

Rat Haptoglobin (HP) ELISA Kit
abx256353-96tests	Abbexa	96 tests	EUR 904.8

Haptoglobin (19-347 a.a) Protein
20-abx262754	Abbexa	Ask for price Ask for price Ask for price	10 ug 1 mg 2 µg

Haptoglobin Protein
20-abx260629	Abbexa	Ask for price Ask for price Ask for price	1 mg 20 ug 5 ug

Dog Haptoglobin (HP) ELISA Kit
abx250008-96tests	Abbexa	96 tests	EUR 1036.8

Pig Haptoglobin (HP) ELISA Kit
abx514090-96tests	Abbexa	96 tests	EUR 943.2

Rat Haptoglobin (HP) ELISA Kit
abx514091-96tests	Abbexa	96 tests	EUR 904.8

Cow Haptoglobin (HP) ELISA Kit
20-abx257182	Abbexa	Ask for price Ask for price Ask for price	10 × 96 tests 5 × 96 tests 96 tests

Cow Haptoglobin (HP) ELISA Kit
20-abx258067	Abbexa	Ask for price Ask for price Ask for price	10 × 96 tests 5 × 96 tests 96 tests

Haptoglobin Protein
20-abx260046	Abbexa	Ask for price Ask for price Ask for price	10 mg 1 mg 200 ug

Dog Haptoglobin (Hpt) CLIA Kit
20-abx492073	Abbexa	Ask for price Ask for price Ask for price	10 × 96 tests 5 × 96 tests 96 tests

Pig Haptoglobin (Hpt) CLIA Kit
20-abx492075	Abbexa	Ask for price Ask for price Ask for price	10 × 96 tests 5 × 96 tests 96 tests

Rat Haptoglobin (Hpt) CLIA Kit
20-abx492076	Abbexa	Ask for price Ask for price Ask for price	10 × 96 tests 5 × 96 tests 96 tests

CLIA kit for Rat HP (Haptoglobin)
E-CL-R0320	Elabscience Biotech	1 plate of 96 wells	EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Rat HP (Haptoglobin) in samples from Serum, Plasma, Cell supernatant

Cat Haptoglobin ELISA Kit
E-20HPT	Immunology Consultants Laboratory	1 x 96 well plate	EUR 553.2

Dog Haptoglobin ELISA Kit
E-40HPT	Immunology Consultants Laboratory	1 x 96 well plate	EUR 529.2

Dog HP/ Haptoglobin ELISA Kit
E0046Do	Sunlong	1 Kit	EUR 630
Description: Zonulin

Pig HP/ Haptoglobin ELISA Kit
E0087Pi	Sunlong	1 Kit	EUR 630
Description: Zonulin

Rat Haptoglobin ELISA kit
E02H0104-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rat Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Haptoglobin ELISA kit
E02H0104-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Rat Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Haptoglobin ELISA kit
E02H0104-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Rat Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Hp/ Haptoglobin ELISA Kit
E0462Ra	Sunlong	1 Kit	EUR 557
Description: Ba1-647,Liver regeneration-related protein LRRG173,Zonulin

Dog Haptoglobin ELISA kit
E08H0104-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Canine Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Haptoglobin ELISA kit
E08H0104-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Canine Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Haptoglobin ELISA kit
E08H0104-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Canine Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Haptoglobin ELISA kit
E07H0104-192T	BlueGene	192 tests	EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Haptoglobin ELISA kit
E07H0104-48	BlueGene	1 plate of 48 wells	EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Haptoglobin ELISA kit
E07H0104-96	BlueGene	1 plate of 96 wells	EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine Haptoglobin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog haptoglobin (HP) Elisa kit
EK762027	AFG Bioscience LLC	96 Wells	EUR 0.94

Rat Hp(Haptoglobin) ELISA Kit
EKF57921-48T	Biomatik Corporation	48T	EUR 396.9

Rat Hp(Haptoglobin) ELISA Kit
EKF57921-5x96T	Biomatik Corporation	5x96T	EUR 2693.25

Rat Hp(Haptoglobin) ELISA Kit
EKF57921-96T	Biomatik Corporation	96T	EUR 567

Rat HP (Haptoglobin) ELISA Kit
EKE62136-5x96T	Biomatik Corporation	5x96T	EUR 3124.08

Rat HP (Haptoglobin) ELISA Kit
EKE62136-96T	Biomatik Corporation	96T	EUR 657.7

Dog HP(Haptoglobin) ELISA Kit
ELK6862-48T	ELK Biotech	48T	Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Dog HP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Dog HP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Dog HP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Dog HP in the samples is then determined by comparing the OD of the samples to the standard curve.

Dog HP(Haptoglobin) ELISA Kit
ELK6862-96T	ELK Biotech	96T	Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Dog HP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Dog HP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Dog HP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Dog HP in the samples is then determined by comparing the OD of the samples to the standard curve.

Pig HP(Haptoglobin) ELISA Kit
ELK5705-48T	ELK Biotech	48T	Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pig HP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Pig HP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Pig HP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Pig HP in the samples is then determined by comparing the OD of the samples to the standard curve.

Pig HP(Haptoglobin) ELISA Kit
ELK5705-96T	ELK Biotech	96T	Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pig HP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Pig HP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Pig HP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Pig HP in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat Haptoglobin ELISA kit
E01A13761	BlueGene	96T	EUR 700
Description: ELISA

Haptoglobin Rabbit pAb
E2381731	EnoGene	100ul	EUR 225
Description: Available in various conjugation types.

Haptoglobin Rabbit pAb
E2251597	EnoGene	100ul	EUR 225
Description: Available in various conjugation types.

Rat Haptoglobin ELISA Kit
EK2286	SAB	96 tests	EUR 599